Trainedbyjp TBJP Cure-Coming 60 servings
TBJP Cure-Coming (60 Servings)
Cure-Coming, an ultra-absorbable curcumin for whole-body health support containing ultra-potent patented BCM-95® Curcumin which has been shown to aid in lowering systemic inflammation, brain/immune/digestive health as well as antioxidant support (60 Servings)
Per Serving
400mg BCM-95® curcumin Tumeric extract
TrainedbyJP Nutrition brings to you Cure-Coming, an ultra-absorbable curcumin for whole-body health support containing ultra-potent patented BCM-95® Curcumin which has been shown to aid in lowering systemic inflammation, brain/immune/digestive health as well as antioxidant support.
Curcumin, the bioactive component of turmeric, Curcuma longa has an exceptionally wide spectrum of activities most notably its antioxidant and anti-inflammatory properties. Most recently, it has also been postulated to have anti-depressive properties in major depressive patients as well as positive cognitive outcomes in older populations.
Curcumin inhibits pro-inflammatory transcription factors such as nuclear factor-kappa beta (NFK- B) which can effect joint inflammation. It also activates peroxisome proliferator–activated receptor gamma (PPAR-γ) and Nrf2 cell signaling pathways, leading to the downregulation of tumor necrosis factor (TNF) and interleukin-6 (IL-6), and upregulates adiponectin (the hormone involved in blood glucose and fatty acid breakdown made by adipose fat tissue).
In simple terms, curcumin has the potential to lower C-Reactive Protein (CRP; a measure of inflammation in the body), induce autophagy through mTOR inhibition (the selective destruction of damaged cellular organelles), protect against cardiac hypertrophy, and potentially decrease artherosclerosis risk.
Despite the promising nutritional and pharmacological properties of curcumin, it exhibits low aqueous solubility, poor gastrointestinal absorption and poor bioavailability.
Its high rate of metabolism, metabolic inactivation and rapid elimination from the body makes it difficult to yield appreciable plasma concentrations. Because of its poor oral absorption, it is difficult for orally administered curcumin to reach blood levels sufficient to exert its bioactivities. Poor absorption from the gut and avid metabolism in the body is cited as reasons for the lack of systemic availability.
To overcome this problem, several curcumin preparations with drug-delivery systems (DDS) have been developed to increase the bioavailability of curcumin after oral administration.
Combinations with piperine have been most common. Piperine, an inhibitor of phase II liver metabolism and intestinal glucuronidation. In rats, the bioavailability of curcumin increased by 154% with piperine compared with a control group without piperine. In humans, piperine (20 mg/kg) was co-administered with curcumin (2 g) and the bioavailability was 20-times that of the control group. However, enhancing bioavailability by inhibiting phase II metabolism must be carefully carried out since many compounds are detoxified through this liver route which may be slowed by adminstering piperine.
BCM-95® is a novel bio-enhanced preparation of curcumin with the addition of phosphatidylcholine and turmeric essential oils (most notably aromatic tumerone volatile oil), which leads to enhanced and sustained absorption. In a human study, 2 g administration showed the bioavailability of BCM-95 (based on curcumin Area Under Curve (AUC)) to be almost 6.93-fold higher than that of a control curcumin formulation with no additive. The half life was shown to be approx. 4.96 h compared to 2.6 h for the control. 2 g/day dose levels are well tolerated without even mild adverse reactions. However, the mechanisms of these enhancements are unknown.
TrainedbyJP Nutrition stands by this long standing patented form of BCM-95® curcumin and we are proud to produce Cure-Coming; a supplement which we believe supports the health of nearly every organ in your body.
Formulated alongside Dr Dean St Mart.
EU SHIPPING TERMS - CLICK HERE
Northern Ireland
Free NI delivery on orders over £50.00
We offer free 2-3 working day delivery for all orders over £50.00
All orders placed before 1p.m. will be processed the same day and delivered accordingly with chosen delivery option. Please note that courier companies work from Monday to Saturday (excluding Bank Holidays).
NI Express delivery is £2.99 and if ordered before 1pm will be delivered next day Mon-Sat only T’s & C’s apply (all our orders will be processed same day if ordered before 1pm. Sometimes the courier can let us down but we guarantee all express items are sent same day if ordered before 1pm).
Shipping on orders under £50.00 will be £2.99 and are 1-2 days delivery sent via recorded signed for post.
For queries on shipping times and order status please email hello@nisupplements.com
Ireland
Free Ireland delivery on orders over £70.00
We offer free 1-2 day delivery for all orders over £70.00 if ordered before 1pm excluding weekends.
Orders over £50 will have a reduced rate of £3.49 sent via Parcelforce/GLS and will be a 1-2 day delivery excluding weekends.
All orders under £50 will get our Express Delivery listed below.
All orders placed before 1p.m. will be processed the same day (excluding weekends) and delivered accordingly with chosen delivery option . Please note that courier companies work from Monday to Friday (excluding Bank Holidays).
Ireland Express delivery is £5.99 and if ordered before 1pm will be delivered next day Mon-Fri only T’s & C’s apply (all our orders will be processed same day if ordered before 1pm. Sometimes the courier can let us down but we guarantee all express items are sent the same day if ordered before 1pm).
Shipping on orders under £50.00 will be £5.99 and are 1-2 day delivery sent via Parcelforce/GLS.
UK Mainland (excluding Highlands and Islands - All options below
1-2 Day delivery (91% delivered next day) if ordered before 1pm. NO SIGNATURE REQUIRED fully tracked. DOES NOT INCLUDE SUNDAYS - £3.49
1-2 Day delivery (91% delivered next day) if ordered before 1pm. SIGNATURE REQUIRED fully tracked. DOES NOT INCLUDE SUNDAYS - £3.99
Orders over £50 can be sent FREE 4-5 day delivery if ordered before 1pm NO SIGNATURE REQUIRED fully tracked. DOES NOT INCLUDE SUNDAYS - FREE
4-5 day delivery if ordered before 1pm SIGNATURE REQUIRED fully tracked. DOES NOT INCLUDE SUNDAYS - FREE
International Shipping
ALL our International Shipping rates are available at checkout.
Please note all delivery time estimates are subject to stock availability and receiving your order by 1pm. Orders placed after 1pm will be processed next working day. Orders are not processed or delivered on weekends and bank holidays.
If for any reason we expect that your order will not arrive within the specified times, we will e-mail or call you shortly after receiving your order. It is therefore very important for you to provide a valid e-mail address and contact number that we can contact you on. Please be sure to check your e-mails and phone messages shortly after placing the order in case we need to contact you.
If an order is returned to us due to customer error (failure to take delivery of the order or arrange a collection/redelivery) then a re-shipping fee is applicable. This is due to the cost of re-packing, and re-shipping that item. A refund of the item minus our shipping costs can be provided as an alternative, but if the error is ours, the item will, of course, be re-shipped at our cost.
Lastly, there is sometimes human error can happen either from ourselves or couriers/delivery companies that we use. It may arrive late; it may arrive damaged; it may not arrive at all. But in any of these cases, we will rectify this with immediate effect directly with yourself and you will get a full refund for any postage you have paid. Incorrect delivery information as stated by the customer is the responsibility of the customer, who will be charged for collection on their behalf.
We try our best to help everyone, but for legal reasons brought about by a minority of our customers, we do need to state that it is the customer's responsibility to ensure that they are present to sign for the parcel. In no way can Blú Nutrition UK, Fastway Couriers, Myhermes, DPD, PARCELFORCE or Royal Mail be held liable for failed deliveries unless either of those parties has been negligent in their duty to deliver.
OUR REFUNDS POLICY
We guarantee your satisfaction with our Products and if, for a reason of manufacturing fault, you are not satisfied with any Product(s) you purchase, we offer a full refund or exchange policy. This is to ensure your satisfaction at all times with our Products.
Without prejudice, you may RETURN AN ITEM PROVIDED THE SEAL IS UNBROKEN, THERE IS NO DAMAGE TO THE PACKAGING AND THE PRODUCT HAS BEEN STORED IN THE RECOMMENDED CONDITIONS. In this case, you will receive a full refund of the price paid for the Product in accordance with our refund policy. This provision does not affect your statutory rights.
When you return a Product to us (for instance, because you have cancelled the Contract between us, or have notified us in that you do not agree to any change in these terms and conditions or in any of our policies, or because you claim that the Product is defective), we will notify you of your refund via letter or e-mail within a reasonable period of time. We will usually refund any money received from you using the same method originally used by you to pay for your purchase. We will usually process the refund due to you as soon as possible and, in any case within 30 days of the day we received your cancellation or the day we confirmed to you via letter or e-mail that you were entitled to a refund FOLLOWING RETURN of the Product.
If the Product is at fault, or packaging is damaged beyond a salvageable state, we will either refund or replace IN LINE WITH TIMESCALES SHOWN IN our terms & conditions. If however, YOU ARE UNHAPPY WITH THE FLAVOUR after a product has been opened, as per government legislation we cannot offer a refund or exchange as supplements are classed as a food product which cannot be resold or used again.
ALL our orders are CCTV captured. If the delivery note says an item should be in your parcel but it isn't, or if you have received an item not ordered, please use our the contact form page to get in touch with us letting us know which item(s) you believe are missing or HAVE BEEN DELIVERED IN ERROR. We can return to our camera's and check exactly what has been placed in the box and what weight the box was scanned at for delivery. You have up to 72 hours to inform us of such an error, outside of 72 hours we will not be able to investigate or assist with this claim.
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